产品目录

本品为来源于兔的抗MATER的多克隆抗体。
宿主：兔
克隆性：多克隆抗体
用途：ICC, IF
交叉反应性：人，小鼠
分子量：134KDa
推荐稀释比例：IF(1:200),ICC(1:200)

About this Antibody
Name	MATER Rabbit Polyclonal Antibody
Category	Polyclonal antibody(pAb); Primary antibody
Isotype	IgG
Purification	Peptide affinity purified
About the Immunogen
Immunogen	This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to MATER.
Gene ID	126206
SwissProt	P59047
Synonyms	NLRP5; NALP5; PAN11; PYPAF8; CLR19.8
Category	-
Background	NLRP5, short for NOD-like receptor family pyrin domain containing 5, is an intracellular protein that plays a role in early embryogenesis. NLRP5 is also known as NACHT, LRR and PYD domains-containing protein 5 (NALP5), Mater protein homolog (MATER), PYPAF8, PAN11, and CLR19.8, and is one of 14 pyrin domain containing members of the NOD-like receptor family of cytoplasmic receptors known to mammals. Conserved oocyte-specific expression of NLRP5 is consistent among many mammalian species. As a member of the subcortical maternal complex (SCMC), it plays an essential role for zygotes to progress nd the first embryonic cell divisions. NLRP5 also localizes to the nuclear envelope and mitochondria in germinal vesicle oocytes, suggesting a possible role in mitochondrial function .

注意事项：
1. 如果本抗体用于Western blot (WB)、免疫荧光(IF)、免疫细胞化学(ICC)等实验，请注意回收使用过的稀释抗体。回收的抗体通常至少可以重复使用5-10次。稀释后的抗体，包括已经使用过的稀释抗体，请4℃保存。
2. 回收后重复使用的抗体，使用方法同新鲜稀释的抗体。如果在重复使用过程中发现抗体出现轻微混浊现象，可以10,000g离心1-3分钟，取上清用于后续检测。如果回收的抗体出现明显的絮状物或长霉长菌等情况，则可以考虑废弃该抗体。
3. 提供的Western一抗稀释液也可以用于免疫荧光(IF)、免疫组化(IHC)、免疫细胞化学(ICC)等适当用途。如果希望获得最佳的检测效果，请考虑使用上述检测专用的一抗稀释液。

储存条件：-20℃，有效期一年。
相关搜索：兔抗MATER抗体，MATER Rabbit Polyclonal Antibody